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          enquirebio 4070-MSM3-P0說(shuō)明書(shū)

          更新時(shí)間:2020-04-28      點(diǎn)擊次數(shù):1571

           

          enquirebio 4070-MSM3-P0說(shuō)明書(shū)

          TACSTD2 / TROP2 (Epithelial Marker) Ultraspecific Antibody 

          TACSTD2 / TROP2(上皮標(biāo)記)超特異性抗體 

          Tested against >20,000 Human Proteins

          Product NumberDescriptionPrice
          4070-MSM3-P0Size: 20 ug, Tag: Unconjugated$ 199.00
          4070-MSM3-P1Size: 100 ug, Tag: Unconjugated$ 429.00
          4070-MSM3-P1ABXSize: 100 ug, Tag: Unconjugated$ 429.00

           

          enQuire Bio Product Logo

          Formalin-fixed, paraffin embedded human colon carcinoma sections stained with 100 ul anti-TROP2 (clone TACSTD2/2153) at 1:300. HIER epitope retrieval prior to staining was performed in 10mM Citrate, pH 6.0.

          Formalin-fixed, paraffin embedded human pancreaticcarcinoma sections stained with 100 ul anti-TROP2 (clone TACSTD2/2153) at 1:200. HIER epitope retrieval prior to staining was performed in 10mM Citrate, pH 6.0.

          Data from SDS-PAGE analysis of Anti-TROP2 antibody (Clone TACSTD2/2153). Reducing lane (R) shows heavy and light chain fragments. NR lane shows intact antibody with expected MW of approximately 150 kDa. The data are consistent with a high purity, intact mAb.

          Formalin-fixed, paraffin-embeddedhuman PancreaticCarcinoma stained with TACSTD2 / TROP2Mouse Monoclonal Antibody (TACSTD2/2153).

          FFPE human pancreatic carcinoma sections stained with 100 ul anti-TROP2 (clone TACSTD2/2153) at 1:400. HIER epitope retrieval prior to staining was performed in 10mM Citrate, pH 6.0.

          Formalin-fixed, paraffin embedded human basal cell carcinoma sections stained with 100 ul anti-TROP2 (clone TACSTD2/2153) at 1:200. HIER epitope retrieval prior to staining was performed in 10mM Citrate, pH 6.0.

          Formalin-fixed, paraffin embedded human colon carcinoma sections stained with 100 ul anti-TROP2 (clone TACSTD2/2153) at 1:300. HIER epitope retrieval prior to staining was performed in 10mM Citrate, pH 6.0.

          Formalin-fixed, paraffin embedded human pancreaticcarcinoma sections stained with 100 ul anti-TROP2 (clone TACSTD2/2153) at 1:200. HIER epitope retrieval prior to staining was performed in 10mM Citrate, pH 6.0.

          Data from SDS-PAGE analysis of Anti-TROP2 antibody (Clone TACSTD2/2153). Reducing lane (R) shows heavy and light chain fragments. NR lane shows intact antibody with expected MW of approximately 150 kDa. The data are consistent with a high purity, intact mAb.

          Formalin-fixed, paraffin-embeddedhuman PancreaticCarcinoma stained with TACSTD2 / TROP2Mouse Monoclonal Antibody (TACSTD2/2153).

          FFPE human pancreatic carcinoma sections stained with 100 ul anti-TROP2 (clone TACSTD2/2153) at 1:400. HIER epitope retrieval prior to staining was performed in 10mM Citrate, pH 6.0.

          Formalin-fixed, paraffin embedded human basal cell carcinoma sections stained with 100 ul anti-TROP2 (clone TACSTD2/2153) at 1:200. HIER epitope retrieval prior to staining was performed in 10mM Citrate, pH 6.0.

           

           

          人抗-TACSTD2 / TROP2(上皮標(biāo)記)抗體產(chǎn)品屬性

          物種:人類

          經(jīng)過(guò)測(cè)試的應(yīng)用程序: IHC。

          克隆性:單克隆

          抗TACSTD2 / TROP2(上皮標(biāo)記)抗體克?。?/strong> TACSTD2 / 2153

          克隆TACSTD2 / 2153宿主和同種型:小鼠IgG1,κ

          抗人類TACSTD2 / TROP2(上皮標(biāo)記)陽(yáng)性對(duì)照樣品: HT29細(xì)胞。乳腺癌或結(jié)腸癌

          抗體TACSTD2 / 2153染色的細(xì)胞定位:細(xì)胞表面

          緩沖液和穩(wěn)定劑: 10mM PBS,含0.05%BSA和0.05%疊氮化物。也可不帶BSA和疊氮化物。

          抗體濃度: 200 ug / ml

          抗體純化方法:從生物反應(yīng)器濃縮物中純化的蛋白A / G。

          免疫原:人TACSTD2蛋白的重組片段(約aa 31-274)(請(qǐng)致電以獲取更多信息。)

          儲(chǔ)存條件:儲(chǔ)存于2至8 C(冷藏)。正確存放后可穩(wěn)定保存24個(gè)月。

          TACSTD2 / TROP2(上皮標(biāo)記)以前觀察到的抗體染色模式

          限制與保證

          inquire Bio的產(chǎn)品TACSTD2 / TROP2(上皮標(biāo)記)單克隆特異性抗體僅供研究使用(僅限于RUO)。正確存放后,保證該抗體可工作兩年。

           

          TACSTD2 / TROP2(上皮標(biāo)記)一般信息備用名細(xì)胞表面糖蛋白Trop-2;膜成分1號(hào)染色體,表面標(biāo)志物1(M1S1);胰腺癌標(biāo)志物蛋白GA733-1; TROP2;腫瘤相關(guān)鈣信號(hào)轉(zhuǎn)導(dǎo)子2(TACSTD2)分子量40kDa的染色體位置在藍(lán)色冰上的船。精選數(shù)據(jù)庫(kù)和生物信息學(xué)數(shù)據(jù)基因符號(hào)4070Entrez基因IDTACSTD2UniProt IDP09758UniGene IDHs23582COSMIC ID鏈接TACSTD2KEGG基因IDhsa:4070TACSTD2 / TROP2(上皮標(biāo)記)的概述。TACSTD2是細(xì)胞表面糖蛋白受體。它是一種單程I型膜蛋白,包含一個(gè)1型甲狀腺球蛋白結(jié)構(gòu)域,一個(gè)表皮生長(zhǎng)因子樣重復(fù)序列,一個(gè)位于C末端附近的磷脂酰肌醇結(jié)合位點(diǎn)和酪氨酸磷酸化位點(diǎn)。它在轉(zhuǎn)導(dǎo)細(xì)胞內(nèi)鈣信號(hào)中發(fā)揮作用。它在滋養(yǎng)細(xì)胞,角膜和復(fù)層上皮細(xì)胞中表達(dá)。它還在幾種類型的腫瘤中高表達(dá),并參與調(diào)節(jié)癌細(xì)胞的生長(zhǎng)。

           

           

           

           

           

           

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